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3-B]PYRIDIN-3-YL]-

Pim1/AKK1-IN-1

CAS: 1093222-27-5

Molecular Formula: C20H13N5O

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3-B]PYRIDIN-3-YL]- - Names and Identifiers

Name Pim1/AKK1-IN-1
Synonyms CS-2864
3-B]PYRIDIN-3-YL]-
3-b]pyridin-3-yl]-
AAK1 DUAL INHIBITOR
3-PYRIDINECARBOXAMIDE
LKB1(AAK1 dual inhibitor)
N-[5-(4-cyanophenyl)-1H-pyrrolo[2
N-[5-(4-CYANOPHENYL)-1H-PYRROLO[2
N-[5-(4-Cyanophenyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]-3-pyridinecarboxamide
CAS 1093222-27-5

3-B]PYRIDIN-3-YL]- - Physico-chemical Properties

Molecular FormulaC20H13N5O
Molar Mass339.35
Density1.42
Solubility 10 mM in DMSO
pKa11.62±0.43(Predicted)
Storage Condition-20℃
In vitro study Pim1/AKK1-IN-1 is multi-kinase inhibitor, and hasK d of 380 nM against LKB1 and 53 nM against AAK1.

3-B]PYRIDIN-3-YL]- - Preparation solution concentration reference

 1mg5mg10mg
1 mM2.947 ml14.734 ml29.468 ml
5 mM0.589 ml2.947 ml5.894 ml
10 mM0.295 ml1.473 ml2.947 ml
5 mM0.059 ml0.295 ml0.589 ml
Last Update:2024-01-02 23:10:35

3-B]PYRIDIN-3-YL]- - Reference Information

biological activity Pim1/AKK1-IN-1 is a potent multi-enzyme inhibitor, can act on Pim1/AKK1/MST2/LKB1,Kd values were 35 nM/53 nM/75 nM/380 nM.
Target Kd: 35 nM (Pim1), 53 nM (AKK1), 75 nM (MST2), 380 nM (LKB1)
in vitro study Pim1/AKK1-IN-1 is multi-kinase inhibitor, and hasK d of 380 nM against LKB1 and 53 nM against AAK1.
Last Update:2024-04-09 20:52:54
3-B]PYRIDIN-3-YL]-
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Shanghai Amole Biotechnology Co., Ltd.
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Product Name: N-(5-(4-Cyanophenyl)-1H-pyrrolo[2,3-b]pyridin-3-yl)nicotinamide Request for quotation
CAS: 1093222-27-5
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Shanghai Amole Biotechnology Co., Ltd.
Spot supply
Product Name: N-(5-(4-Cyanophenyl)-1H-pyrrolo[2,3-b]pyridin-3-yl)nicotinamide Request for quotation
CAS: 1093222-27-5
Tel: 400-968-2212
Email: 3623107365@qq.com
Mobile: 18916960931
QQ: 3623107365 Click to send a QQ message
Wechat: 18916960931
Shanghai Macklin Biochemical Co., Ltd
Spot supply
Product Name: Pim1/AKK1-IN-1 Visit Supplier Webpage Request for quotation
CAS: 1093222-27-5
Tel: +86-18821248368
Email: Int06@meryer.com
Mobile: +86-18821248368
QQ: 495145328 Click to send a QQ message
WhatsApp: +86-18821248368
SHANGHAI ACMEC BIOCHEMICAL TECHNOLOGY CO., LTD.
Spot supply
Product Name: Pim1/AKK1-IN-1 Visit Supplier Webpage Request for quotation
CAS: 1093222-27-5
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922 Click to send a QQ message
Wechat: 18621343501
WhatsApp: +86-18621343501
MedChemExpress (MCE)
Spot supply
Product Name: LKB1/AAK1 dual inhibitor Visit Supplier Webpage Request for quotation
CAS: 1093222-27-5
Tel: 609-228-6898
Email: sales@medchemexpress.com
     tech@medchemexpress.com
Mobile: 609-228-6898
BOC Sciences
Spot supply
Product Name: LKB1/AAK1 dual inhibitor Visit Supplier Webpage Request for quotation
CAS: 1093222-27-5
Tel: +16314854226
Email: info@bocsci.com
Mobile: +16314854226
Linkedin: https://www.linkedin.com/company/boc-sciences
Product List: View Catalog
Shanghai Yuanye Bio-Technology Co., Ltd.
Spot supply
Product Name: Pim1/AKK1-IN-1 Visit Supplier Webpage Request for quotation
CAS: 1093222-27-5
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409 Click to send a QQ message
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